Article
A biomarker-based mathematical model to predict bone-forming potency of human synovial and periosteal mesenchymal stem cells.
Arthritis and rheumatism - 1 Jan 2008
De Bari Cosimo, Dell'Accio Francesco, Karystinou Alexandra, Guillot Pascale V, Fisk Nicholas M, Jones Elena A, McGonagle Dennis, Khan Ilyas M, Archer Charles W, Mitsiadis Thimios A, Donaldson Ana Nora, Luyten Frank P, Pitzalis Costantino
Abstract excerpt
OBJECTIVE: To develop a biomarker-based model to predict osteogenic potency of human mesenchymal stem cells (MSCs) from synovial membrane and periosteum. METHODS: MSC populations were derived from adult synovium and periosteum. Phenotype analysis was performed by fluorescence-activated cell sorting and real-time reverse transcriptase-polymerase chain reaction (RT-PCR). Telomere lengths were determined by Southern...
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