Article
The fibroid phenotype of biological naïve patients with rheumatoid arthritis are less likely to respond to anti-IL-6R treatment.
Scientific reports - 10 May 2024
Madsen Sofie Falkenløve, Sinkeviciute Dovile, Thudium Christian S, Karsdal Morten A, Bay-Jensen Anne-Christine
Abstract excerpt
Type III collagen gene expression is upregulated in the synovium of patients with rheumatoid arthritis (RA) presenting the fibroid phenotype. The soluble type III collagen formation biomarker, PRO-C3, is known to measure fibrogenesis in fibrotic diseases. In this exploratory study, we aimed to investigate the association between fibrogenesis (PRO-C3) and the disease- and treatment response in patients with RA. We...
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