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Article

IL-6-dependent PGE2 secretion by mesenchymal stem cells inhibits local inflammation in experimental arthritis.

PloS one - 7 Dec 2010

Bouffi Carine, Bony Claire, Courties Gabriel, Jorgensen Christian, Noël Danièle

Abstract excerpt

BACKGROUND: Based on their capacity to suppress immune responses, multipotent mesenchymal stromal cells (MSC) are intensively studied for various clinical applications. Although it has been shown in vitro that the immunomodulatory effect of MSCs mainly occurs through the secretion of soluble medi...

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Identifiers

PMID: 21151872
DOI: 10.1371/journal.pone.0014247
PMCID: PMC2998425

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21151872-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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