Article
Association Analysis of Polymorphisms in TOMM40, CR1, PVRL2, SORL1, PICALM, and 14q32.13 Regions in Colombian Alzheimer Disease Patients.
Alzheimer disease and associated disorders - 1 Jan 2000
Ortega-Rojas Jenny, Morales Luis, Guerrero Esneyder, Arboleda-Bustos Carlos E, Mejia Adriana, Forero Diego, Lopez Luis, Pardo Rodrigo, Arboleda Gonzalo, Yunis Juan, Arboleda Humberto
Abstract excerpt
OBJECTIVE: We evaluated the association of several single-nucleotide polymorphisms in different genes including APOE, TOMM40, CR1, PVRL2, SORL1, PICALM, and GWA_14q32.13 in a Colombian sample of Late-Onset Alzheimer disease (LOAD) patients. METHODS: A case-control study was conducted in 362 individuals (181 LOADs and 181 controls) to determine the association of single-nucleotide polymorphisms in APOE (e2, e3,...
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