The TOMM40 gene rs2075650 polymorphism contributes to Alzheimer's disease in Caucasian, and Asian populations.

doi:10.1016/j.neulet.2016.05.050

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The TOMM40 gene rs2075650 polymorphism contributes to Alzheimer's disease in Caucasian, and Asian populations.

Neuroscience letters - 15 Aug 2016

Huang Hao, Zhao Jun, Xu Biyun, Ma Xu, Dai Qiaoyun, Li Taishun, Xue Fangjing, Chen Bingwei

Abstract excerpt

Largescale genome-wide association studies (GWAS) showed that the TOMM40 rs2075650 polymorphism is significantly associated with Alzheimer's disease (AD) in Caucasian ancestry and Asian population. Here, we evaluated this association with large-scale samples from selected 12 studies (N=28,515; 10,358 cases and 18,157 controls) through the PubMed, AlzGene, and Google Scholar. We identified a significant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Membrane Transport Proteins

Share to Mitochondrial Precursor Protein Import Complex Proteins

Share to Polymorphism, Single Nucleotide

Share to White People

Source

Open in PubMed

Identifiers

PMID: 27328316
DOI: 10.1016/j.neulet.2016.05.050

Genes

TOMM40

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The TOMM40 gene rs2075650 polymorphism contributes to Alzheimer's disease in Caucasian, and Asian populations.PMID 27328316Read ↗

Meta-analysis of the rs2075650 polymorphism and risk of Alzheimer disease.Semantic proximity Read ↗

TOMM40 and APOE variants synergistically increase the risk of Alzheimer's disease in a Chinese population.Semantic proximity Read ↗

Interaction effects between variants in TOMM40 and PVRL2 with plasma amyloid-β and Alzheimer's disease among Chinese older adults: a population-based studySemantic proximity Read ↗

TOMM40 Genetic Variants Cause Neuroinflammation in Alzheimer's Disease.Semantic proximity Read ↗

Association of TOMM40 polymorphisms with late-onset Alzheimer's disease in a Northern Han Chinese population.Semantic proximity Read ↗

TOMM40 rs2075650 polymorphism shows no association with neovascular age-related macular degeneration or polypoidal choroidal vasculopathy in a Chinese population.Semantic proximity Read ↗

New Genetic Associations Between Alzheimer's Disease and Its Key Risk Factors.Semantic proximity Read ↗

The MTHFR C677T polymorphism contributes to increased risk of Alzheimer's disease: evidence based on 40 case-control studies.Semantic proximity Read ↗

TOMM40 and APOE Gene Expression and Cognitive Decline in Japanese Alzheimer’s Disease SubjectsSemantic proximity Read ↗

Alzheimer's disease pathology explains association between dementia with Lewy bodies and APOE‐ε4/TOMM40 long poly‐T repeat allele variantsSemantic proximity Read ↗

TMEM106B and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in Han Chinese.Semantic proximity Read ↗

Association Analysis of Polymorphisms in TOMM40, CR1, PVRL2, SORL1, PICALM, and 14q32.13 Regions in Colombian Alzheimer Disease Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.