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Article

TLR3 Agonist Poly-IC Induces IL-33 and Promotes Myelin Repair.

PloS one - 1 Jan 2016

Natarajan Chandramohan, Yao Song-Yi, Sriram Subramaniam

Abstract excerpt

BACKGROUND: Impaired remyelination of demyelinated axons is a major cause of neurological disability. In inflammatory demyelinating disease of the central nervous system (CNS), although remyelination does happen, it is often incomplete, resulting in poor clinical recovery. Poly-IC a known TLR3 agonist and IL-33, a cytokine which is induced by poly-IC are known to influence recovery and promote repair in...

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Source

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Identifiers

PMID: 27022724
DOI: 10.1371/journal.pone.0152163
PMCID: PMC4811556

Genes

TLR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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