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Article

Toll-like receptor 3 differently modulates inflammation in progressive or benign multiple sclerosis.

Clinical immunology (Orlando, Fla.) - 1 Jan 2014

Saresella Marina, Gatti Andrea, Tortorella Paola, Marventano Ivana, Piancone Federica, La Rosa Francesca, Caputo Domenico, Rovaris Marco, Biasin Mara, Clerici Mario

Abstract excerpt

TLR-dependent signal transduction pathways were analyzed in patients with a diagnosis of either relapsing-remitting (RRMS), secondary progressive (PMS) or benign (BMS) MS and healthy controls (HC). Prototypical TLR molecules expressed either on the cell surface (TLR4) or intracellularly (TLR3) were stimulated with specific antigens (LPS and poly I:C, respectively). Expression of factors involved in TLR signaling...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24334148
DOI: 10.1016/j.clim.2013.10.012

Genes

TLR3
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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