Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Model for the Molecular Mechanism of an Engineered Light-Driven Protein Machine.

Structure (London, England : 1993) - 5 Apr 2016

Hoersch Daniel, Kortemme Tanja

Abstract excerpt

Controllable protein-based machines and materials are of considerable interest for diverse biotechnological applications. We previously re-engineered an ATP-driven protein machine, a group II chaperonin, to function as a light-gated nanocage. Here we develop and test a model for the molecular mechanism of the re-engineered chaperonin, which undergoes a large-scale closed to open conformational change triggered by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Azo Compounds
Share to Binding Sites
Share to Computer Simulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cross-Linking Reagents

Share to Cryoelectron Microscopy

Share to Protein Conformation

Share to Protein Engineering

Source

Identifiers

PMID: 27021162
DOI: 10.1016/j.str.2016.02.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Model for the Molecular Mechanism of an Engineered Light-Driven Protein Machine.PMID 27021162Read ↗

Design of Light-Controlled Protein Conformations and Functions.Semantic proximity Read ↗

A Single-Chain Photoswitchable CRISPR-Cas9 Architecture for Light-Inducible Gene Editing and Transcription.Semantic proximity Read ↗

Regioselective photocyclodimerization of 2-anthracenecarboxylic acid through ATP hydrolysis-driven conformational change using simulation prediction-designed GroEL mutant.Semantic proximity Read ↗

Mechanism and energetics of green fluorescent protein chromophore synthesis revealed by trapped intermediate structures.Semantic proximity Read ↗

Creating Red Light-Controlled Protein Dimerization Systems as Genetically Encoded Actuators with High SpecificitySemantic proximity Read ↗

Engineering protein assemblies with allosteric control via monomer fold-switching.Semantic proximity Read ↗

Differential regulation of protein subdomain activity with caged bivalent ligands.Semantic proximity Read ↗

Chromophore chemistry of fluorescent proteins controlled by light.Semantic proximity Read ↗

A hinge migration mechanism unlocks the evolution of green-to-red photoconversion in GFP-like proteins.Semantic proximity Read ↗

Complete shift of ferritin oligomerization toward nanocage assembly via engineered protein-protein interactions.Semantic proximity Read ↗

De novo design of small-molecule–induced conformational changeSemantic proximity Read ↗

Capturing the photo-signaling state of a photoreceptor in a steady-state fashion by binding a transition metal complex.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.