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Article

A SNaPshot of potentially personalized care: Molecular diagnostics in gynecologic cancer.

Gynecologic oncology - 1 Apr 2016

Penson R T, Sales E, Sullivan L, Borger D R, Krasner C N, Goodman A K, del Carmen M G, Growdon W B, Schorge J O, Boruta D M, Castro C M, Dizon D S, Birrer M J

Abstract excerpt

BACKGROUND: Genetic abnormalities underlie the development and progression of cancer, and represent potential opportunities for personalized cancer therapy in Gyn malignancies. METHODS: We identified Gyn oncology patients at the MGH Cancer Center with tumors genotyped for a panel of mutations by SNaPshot, a CLIA approved assay, validated in lung cancer, that uses SNP genotyping in degraded DNA from FFPE tissue to...

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Source

Identifiers

PMID: 27016236
DOI: 10.1016/j.ygyno.2016.02.032

Genes

AKT1
APC
BRAF
CTNNB1
EGFR
ERBB2
IDH1
KIT
KRAS
NOTCH1
NRAS
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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