Article
Clinical utility of comprehensive liquid molecular profiling in patients with advanced endometrial cancer.
Cancer - 1 Oct 2024
Blanc-Durand Félix, Camilleri Geraldine M, Bayle Arnaud, Aldea Mihaela, Vasseur Damien, Ouali Kaissa, Michels Judith, Pautier Patricia, Nicotra Claudio, Ngo-Camus Maud, Lacroix Ludovic, Rouleau Etienne, Ponce-Aix Santiago, Italiano Antoine, Leary Alexandra
Abstract excerpt
BACKGROUND: Molecular characterization has significantly improved the management of advanced endometrial cancer (EC). It distinguishes four molecular subclasses associated with prognosis and personalized therapeutic strategies. This study assesses the clinical utility of cell-free DNA (cfDNA) profiling in EC to identify targetable alterations. METHODS: Women with metastatic or recurrent EC were prospectively...
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