Article
Applying Precision Medicine to Ovarian Cancer: Proof-of-Principle for a "Molecular Second Look".
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Mar 2018
Schwartz Melissa, Camacho-Vanegas Olga, Wood Ashley M, Dashkoff Matthew, Whitelock Courtney, Harkins Timothy T, Cohen Carmel J, Beddoe Ann Marie, Dottino Peter, Martignetti John A
Abstract excerpt
OBJECTIVES: The objectives of this study were to assess if targeted investigation for tumor-specific mutations by ultradeep DNA sequencing of peritoneal washes of ovarian cancer patients after primary surgical debulking and chemotherapy, and clinically diagnosed as disease free, provides a more sensitive and specific method to assess actual treatment response and tailor future therapy and to compare this...
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