Article
Molecular profiling of gynecologic cancers for treatment and management of disease - demonstrating clinical significance using the AMP/ASCO/CAP guidelines for interpretation and reporting of somatic variants.
Cancer genetics - 1 Apr 2020
Nie Qian, Omerza Gregory, Chandok Harshpreet, Prego Matthew, Hsiao Meng-Chang, Meyers Bridgette, Hesse Andrew, Uvalic Jasmina, Soucy Melissa, Bergeron Daniel, Peracchio Michael, Burns Shelbi, Kelly Kevin, Rowe Shannon, Rueter Jens, Reddi Honey V
Abstract excerpt
Molecular features of gynecologic cancers have been investigated in comprehensive studies, but correlation of these molecular signatures with clinical significance for precision medicine is yet to be established. Towards this end, we evaluated 95 gynecologic cancer cases submitted for testing using The JAX ActionSeq™ NGS panel. Molecular profiles were studied and compared to TCGA datasets to identify similarities...
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