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Article

Evolution of Protein Quaternary Structure in Response to Selective Pressure for Increased Thermostability.

Journal of molecular biology - 5 Jun 2016

Fraser Nicholas J, Liu Jian-Wei, Mabbitt Peter D, Correy Galen J, Coppin Chris W, Lethier Mathilde, Perugini Matthew A, Murphy James M, Oakeshott John G, Weik Martin, Jackson Colin J

Abstract excerpt

Oligomerization has been suggested to be an important mechanism for increasing or maintaining the thermostability of proteins. Although it is evident that protein-protein contacts can result in substantial stabilization in many extant proteins, evidence for evolutionary selection for oligomerization is largely indirect and little is understood of the early steps in the evolution of oligomers. A...

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Identifiers

PMID: 27016206
DOI: 10.1016/j.jmb.2016.03.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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