Article
Identification and characterization of an endoplasmic reticulum localization motif.
Biochemical and biophysical research communications - 22 Apr 2016
Nie Yong-Wei, Wang Meng, Zhang Ping, Huan Lei, Liu Dong-Jun
Abstract excerpt
Sorting motifs are involved in the transport of diverse proteins. In the present study, we identified a hydrophobic peptide (WRPWRNFWWSIRVPWRRN) that was able to target enhanced green fluorescent protein- or DsRed2-enriched vesicular-like sub-compartments of the endoplasmic reticulum (ER). Analysis of mutation constructs revealed that the sequence WRPWRNFWW was responsible for the ER-targeting activity, and the...
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