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Article

ER export of ERGIC-53 is controlled by cooperation of targeting determinants in all three of its domains.

Journal of cell science - 1 Nov 2003

Nufer Oliver, Kappeler Felix, Guldbrandsen Svend, Hauri Hans-Peter

Abstract excerpt

Selective export of proteins from the endoplasmic reticulum (ER) requires transport signals that have not been fully characterized. Here, we provide the first complete map of ER export determinants of a type I membrane protein, ERGIC-53, that cycles in the early secretory pathway. ER export requires a phenylalanine motif at the C-terminus, known to mediate coat protein II (COPII) interaction, that is assisted by...

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Identifiers

PMID: 13130098
DOI: 10.1242/jcs.00759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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