Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel cargo-binding site in the beta and delta subunits of coatomer.

The Journal of cell biology - 22 Oct 2007

Michelsen Kai, Schmid Volker, Metz Jutta, Heusser Katja, Liebel Urban, Schwede Torsten, Spang Anne, Schwappach Blanche

Abstract excerpt

Arginine (R)-based ER localization signals are sorting motifs that confer transient ER localization to unassembled subunits of multimeric membrane proteins. The COPI vesicle coat binds R-based signals but the molecular details remain unknown. Here, we use reporter membrane proteins based on the proteolipid Pmp2 fused to GFP and allele swapping of COPI subunits to map the recognition site for R-based signals. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arginine
Share to Coatomer Protein
Share to Conserved Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Endoplasmic Reticulum

Share to Mutant Proteins

Share to Protein Sorting Signals

Share to Protein Subunits

Share to Structural Homology, Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 17954604
DOI: 10.1083/jcb.200704142
PMCID: PMC2064757

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel cargo-binding site in the beta and delta subunits of coatomer.PMID 17954604Read ↗

Assembly, organization, and function of the COPII coatSemantic proximity Read ↗

COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP.Semantic proximity Read ↗

Identification and characterization of an endoplasmic reticulum localization motif.Semantic proximity Read ↗

Dsl1p, an essential component of the Golgi-endoplasmic reticulum retrieval system in yeast, uses the same sequence motif to interact with different subunits of the COPI vesicle coat.Semantic proximity Read ↗

Coatomer interaction with di-lysine endoplasmic reticulum retention motifs.Semantic proximity Read ↗

COP-binding sites in p24delta2 are necessary for proper secretory cargo biosynthesis.Semantic proximity Read ↗

Rer1p, a retrieval receptor for endoplasmic reticulum membrane proteins, is dynamically localized to the Golgi apparatus by coatomer.Semantic proximity Read ↗

Consequences of mutations in the genes of the ER export machinery COPII in vertebrates.Semantic proximity Read ↗

Coatopathies: Genetic Disorders of Protein CoatsSemantic proximity Read ↗

Traffic COPs of the Early Secretory PathwaySemantic proximity Read ↗

Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum.Semantic proximity Read ↗

Delta- and zeta-COP, two coatomer subunits homologous to clathrin-associated proteins, are involved in ER retrieval.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.