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Article

Absence of Association Between Sickle Trait Hemoglobin and Placental Malaria Outcomes.

The American journal of tropical medicine and hygiene - 4 May 2016

Patel Jaymin C, Mwapasa Victor, Kalilani Linda, Ter Kuile Feiko O, Khairallah Carole, Thwai Kyaw L, Meshnick Steven R, Taylor Steve M

Abstract excerpt

Heterozygous hemoglobin S (HbAS), or sickle trait, protects children from life-threatening falciparum malaria, potentially by attenuating binding of Plasmodium-infected red blood cells (iRBCs) to extracellular ligands. Such binding is central to the pathogenesis of placental malaria (PM). We hypothesized that HbAS would be associated with reduced risks of PM and low birth weight (LBW). We tested this hypothesis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27001763
DOI: 10.4269/ajtmh.15-0672
PMCID: PMC4856594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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