Article
Heterozygous HbAC but not HbAS is associated with higher newborn birthweight among women with pregnancy-associated malaria.
Scientific reports - 3 May 2017
Tétard Marilou, Milet Jacqueline, Dechavanne Sébastien, Fievet Nadine, Dorin-Semblat Dominique, Elion Jacques, Fairhurst Rick M, Deloron Philippe, Tuikue-Ndam Nicaise, Gamain Benoît
Abstract excerpt
Pregnancy-associated malaria (PAM) is associated with poor pregnancy outcomes. Hemoglobin S (HbS) and hemoglobin C (HbC) mutations are frequently encountered in malaria-endemic areas of Africa, where they protect children from severe and uncomplicated Plasmodium falciparum malaria. However, scant epidemiological data exist on the impact of these Hb variants on PAM. A prospective cohort of 635 Beninese pregnant...
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