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Article

Age-Related Changes in Malaria Clinical Phenotypes During Infancy Are Modified by Sickle Cell Trait.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 16 Nov 2021

Zehner Nicholas, Adrama Harriet, Kakuru Abel, Andra Teddy, Kajubi Richard, Conrad Melissa, Nankya Felistas, Clark Tamara D, Kamya Moses, Rodriguez-Barraquer Isabel, Dorsey Grant, Jagannathan Prasanna

Abstract excerpt

BACKGROUND: Infants are protected against Plasmodium falciparum malaria. Mechanisms that drive this protection remain unclear due to a poor understanding of malaria clinical phenotypes during infancy. METHODS: We enrolled a birth cohort of 678 infants in Busia, Uganda, an area of high malaria transmission. We followed infants through 12 months of age and quantified protection against parasitemia and clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33738485
DOI: 10.1093/cid/ciab245
PMCID: PMC8599196

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