Article
The Staphylococcus aureus LytSR two-component regulatory system affects biofilm formation.
Journal of bacteriology - 1 Aug 2009
Sharma-Kuinkel Batu K, Mann Ethan E, Ahn Jong-Sam, Kuechenmeister Lisa J, Dunman Paul M, Bayles Kenneth W
Abstract excerpt
Studies of the Staphylococcus aureus LytSR two-component regulatory system have led to the identification of the cid and lrg operons, which affect murein hydrolase activity, stationary-phase survival, antibiotic tolerance, and biofilm formation. The cid gene products enhance murein hydrolase activity and antibiotic tolerance whereas the lrg gene products inhibit these processes in a manner believed to be...
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