Mutation hot spots in hepatitis B surface antigen in chronic carriers from Khoozestan province, southern of Iran.

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Article

Mutation hot spots in hepatitis B surface antigen in chronic carriers from Khoozestan province, southern of Iran.

Iranian journal of allergy, asthma, and immunology - 13 Jul 2013

Ramezani Fatemeh, Norouzi Mehdi, Sarizade Gholam Reza, Poortahmasebi Vahdat, Kalantar Ebrahim, Magnius Lars, Norder Helen, Domingo Esteban, Jazayeri Seyed Mohammad

Abstract excerpt

Mutations in the human hepatitis B virus (HBV) genome contribute to its escape from host immune surveillance and result in persistent infections. The aim of this study was to characterize the molecular variations of the surface gene and protein in chronically-infected patients from the southern part of Iran. The surface genes from 12 HBV chronic carriers were amplified, sequenced and subsequently aligned using...

Topics

Amino Acid Substitution
Carrier State
Cross-Sectional Studies
Epitopes, B-Lymphocyte
Epitopes, T-Lymphocyte
Genotype
Hepatitis B Surface Antigens
Humans
Iran
Mutation
Phylogeny

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Open in PubMed

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PMID: 23893811

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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