Article
Prevalence of mutations within major hydrophilic region of hepatitis B virus and their correlation with genotypes among chronically infected patients in Egypt.
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology - 1 Mar 2016
Abu Zeid Walaa M, Ramadan Dalia I, Shemis Mohamed A
Abstract excerpt
BACKGROUND AND STUDY AIMS: Mutations within the major hydrophilic region (MHR) of the hepatitis B surface antigen (HBsAg) have been reported in relation to viral persistence by evasion from vaccine and immunotherapy, severity of liver disease and lack of detection by commercial kits. The aim of this study was to elucidate the circulation of hepatitis B virus (HBV) genotypes, subgenotypes and serotypes in Egypt,...
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