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Article

CHRNA5/A3/B4 Variant rs3743078 and Nicotine-Related Phenotypes: Indirect Effects Through Nicotine Craving.

Journal of studies on alcohol and drugs - 1 Mar 2016

Shmulewitz Dvora, Meyers Jacquelyn L, Wall Melanie M, Aharonovich Efrat, Frisch Amos, Spivak Baruch, Weizman Abraham, Edenberg Howard J, Gelernter Joel, Hasin Deborah S

Abstract excerpt

OBJECTIVE: Nicotine craving is considered an important element in the persistence of cigarette smoking, but little is known about the role of craving in the widely recognized association between variants mapped to the neuronal nicotinic acetylcholine receptor (CHRN) genes on chromosome 15 and nicotine phenotypes. METHOD: The associations between CHRNA5-CHRNA3-CHRNB4 variants and cigarettes per day (CPD), the...

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Topics

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Share to CHRNB4 gene
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nerve Tissue Proteins

Share to Phenotype

Share to Receptors, Nicotinic

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Source

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Identifiers

PMID: 26997181
DOI: 10.15288/jsad.2016.77.227
PMCID: PMC4803655

Genes

CPD
CHRNA3
CHRNA5
CHRNB4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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