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Article

Impact of the HLA-B(*)58:01 Allele and Renal Impairment on Allopurinol-Induced Cutaneous Adverse Reactions.

The Journal of investigative dermatology - 1 Jul 2016

Ng Chau Yee, Yeh Yu-Ting, Wang Chuang-Wei, Hung Shuen-Iu, Yang Chih-Hsun, Chang Ya-Ching, Chang Wan-Chun, Lin Yu-Jr, Chang Chee-Jen, Su Shih-Chi, Fan Wen-Lang, Chen Der-Yuan, Wu Yeong-Jian Jan, Tian Ya-Chung, Hui Rosaline Chung-Yee, Chung Wen-Hung

Abstract excerpt

Allopurinol, a common drug for treating hyperuricemia, is associated with cutaneous adverse drug reactions ranging from mild maculopapular exanthema to life-threatening severe cutaneous adverse reactions, including drug reaction with eosinophilia and systemic symptoms, Stevens-Johnson syndrome, and toxic epidermal necrolysis. We have previously reported that HLA-B*58:01 is strongly associated with...

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Identifiers

PMID: 26996548
DOI: 10.1016/j.jid.2016.02.808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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