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Article

Complementary assays for monitoring susceptibility of varicella-zoster virus resistance to antivirals.

Journal of virological methods - 1 Jul 2016

Perrier Marine, Désiré Nathalie, Deback Claire, Agut Henri, Boutolleau David, Burrel Sonia

Abstract excerpt

The emergence of varicella-zoster virus (VZV) resistance to current antivirals as acyclovir (ACV) constitutes a hindrance to antiviral treatment effectiveness of VZV infections, especially in immunocompromised patients. The molecular mechanisms of VZV resistance reported so far rely on the presence of mutations within thymidine kinase (TK, ORF36) and DNA polymerase (ORF28) viral genes. The aim of this work was to...

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Identifiers

PMID: 26994966
DOI: 10.1016/j.jviromet.2016.03.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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