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Article

Resistance testing of clinical herpes simplex virus type 2 isolates collected over 4 decades.

International journal of medical microbiology : IJMM - 1 Oct 2015

Bohn-Wippert Kathrin, Schmidt Susanne, Runtze Anna, Zell Roland, Sauerbrei Andreas

Abstract excerpt

There is only little information about the role of mutations of the thymidine kinase (TK) and DNA polymerase (pol) genes of herpes simplex virus type 2 (HSV-2) for the development of antiviral resistance. In this study, the polymorphism of TK and DNA pol genes was examined in 82 clinical isolates collected routinely between 1973 and 2013. If novel, presently unclear or resistance-related mutations were found, the...

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PMID: 26338148
DOI: 10.1016/j.ijmm.2015.08.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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