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Article

Genetic polymorphism of thymidine kinase (TK) and DNA polymerase (pol) of clinical varicella-zoster virus (VZV) isolates collected over three decades.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Oct 2017

Hoffmann Anja, Döring Kristin, Seeger Natalja Tatjana, Bühler Martina, Schacke Michael, Krumbholz Andi, Sauerbrei Andreas

Abstract excerpt

BACKGROUND: Genotypic resistance testing of varicella-zoster virus (VZV) strains to antivirals is of high relevance in immunocompromised patients with VZV reactivations unresponsive to therapy. However, the knowledge on mutations associated with natural gene polymorphism or resistance is limited. OBJECTIVES: To examine the genotype of the thymidine kinase (TK) and DNA polymerase (pol) of unselected clinical VZV...

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Identifiers

PMID: 28886462
DOI: 10.1016/j.jcv.2017.08.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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