Article
A Surfactant-Induced Functional Modulation of a Global Virulence Regulator from Staphylococcus aureus.
PloS one - 1 Jan 2016
Mandal Sukhendu, Mahapa Avisek, Biswas Anindya, Jana Biswanath, Polley Soumitra, Sau Keya, Sau Subrata
Abstract excerpt
Triton X-100 (TX-100), a useful non-ionic surfactant, reduced the methicillin resistance in Staphylococcus aureus significantly. Many S. aureus proteins were expressed in the presence of TX-100. SarA, one of the TX-100-induced proteins, acts as a global virulence regulator in S. aureus. To understand the effects of TX-100 on the structure, and function of SarA, a recombinant S. aureus SarA (rSarA) and its...
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