Article
Structural analysis of the antibiotic-recognition mechanism of MarR proteins
15 May 2013
Abstract excerpt
Staphylococci cause a wide range of diseases in humans and animals, and the proteins of the multiple antibiotic-resistance repressor (MarR) family in staphylococci function as regulators of protein expression and confer resistance to multiple antibiotics. Diverse mechanisms such as biofilm formation, drug transport, drug modification etc. are associated with this resistance. In this study, crystal structures of...
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