Article
Relationship between CYP17 gene polymorphisms and risk of prostate cancer.
Genetics and molecular research : GMR - 26 Feb 2016
Song J, Tao Z-H, Liu X-Y, Gong S, Gan L
Abstract excerpt
Cytochrome P450 17a-hydroxylase (CYP17) plays a critical role in androgen biosynthesis. Polymorphisms of the CYP17 promoter have been proposed as risk factors for prostate cancer; however, some studies have produced inconclusive or controversial results. We investigated the relationship between polymorphisms of the CYP17 gene and the risk of prostate cancer. A total of 176 patients with prostate cancer were...
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