Article
Cyp17 genetic polymorphism in prostate cancer and benign prostatic hyperplasia.
Research communications in molecular pathology and pharmacology - 1 Jan 2003
Tigli Hulya, Yazici Hulya, Dalay Nejat
Abstract excerpt
Steroid hormones, especially androgens, are believed to play a key role in the etiology of prostate cancer. Therefore, polymorphisms in genes involved in the androgen metabolism may affect the risk of prostate cancer. One such gene is CYP17, which encodes the cytochrome P450c17alpha enzyme that m...
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