Article
Controversial opinion: evaluation of EGR1 and LAMA2 loci for high myopia in Chinese populations.
Journal of Zhejiang University. Science. B - 1 Mar 2016
Lin Fang-yu, Huang Zhu, Lu Ning, Chen Wei, Fang Hui, Han Wei
Abstract excerpt
Functional studies have suggested the important role of early growth response 1 (EGR1) and Laminin α2-chain (LAMA2) in human eye development. Genetic studies have reported a significant association of the single nucleotide polymorphism (SNP) in the LAMA2 gene with myopia. This study aimed to evaluate the association of the tagging SNPs (tSNPs) in the EGR1 and LAMA2 genes with high myopia in two independent Han...
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