Article
The association of a single nucleotide polymorphism in the promoter region of the LAMA1 gene with susceptibility to Chinese high myopia.
Molecular vision - 22 Apr 2011
Zhao Yan Yan, Zhang Feng Ju, Zhu Si Quan, Duan Hui, Li Yang, Zhou Zhong Jun, Ma Wen Xian, Li Wang Ning
Abstract excerpt
PURPOSE: High myopia is a severe hereditary ocular disease leading to blindness. LAMA1 (alpha subunit of laminin) is a promising candidate gene for high myopia present in the MYP2 (myopia 2) region. The purpose of this study was to determine if high myopia is associated with single nucleotide polymorphism (SNP) variants in LAMA1 in Chinese subjects. METHODS: Ninety-seven Chinese subjects with high myopia and...
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