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Article

Investigation of the association between all-trans-retinol dehydrogenase (RDH8) polymorphisms and high myopia in Chinese.

Journal of Zhejiang University. Science. B - 1 Nov 2010

Yu Yan-shu, Wang Lin-ling, Shen Ye, Yap Maurice K H, Yip Shea-ping, Han Wei

Abstract excerpt

Retinoic acid level in the retina/choroid is altered in induced myopia models. All-trans-retinol dehydrogenase (RDH8) is an important enzyme of retinoic acid metabolism. This study aimed to investigate the association of the RDH8 gene with high myopia. Three single nucleotide polymorphisms (SNPs) [RDH851 (rs2233789), RDH8E5a (rs1644731), and RDH855b (rs3760753)] were selected, based on the linkage disequilibrium...

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Source

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Identifiers

PMID: 21043051
DOI: 10.1631/jzus.B1000001
PMCID: PMC2970892

Genes

RDH8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Investigation of the association between all-trans-retinol dehydrogenase (RDH8) polymorphisms and high myopia in Chinese.PMID 21043051Read ↗

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