Article
Evaluation of EGR1 as a candidate gene for high myopia.
Molecular vision - 15 Jul 2008
Li Tuo, Xiao Xueshan, Li Shiqiang, Xing Yiqiao, Guo Xiangming, Zhang Qingjiong
Abstract excerpt
PURPOSE: EGR1 (OMIM 128990) is an early growth response gene that has been shown to be related to myopia by upregulation and down-regulation of axial eye growth in experimentally induced chicken myopia and knockout mice. The purpose of this study was to test whether variations in the human EGR1 gene are related to high myopia. METHODS: Genomic DNA was prepared from leukocytes of peripheral blood. Cycle sequencing...
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