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Article

Insulin-like growth factor 1 is not associated with high myopia in a large Japanese cohort.

Molecular vision - 1 Jan 2013

Miyake Masahiro, Yamashiro Kenji, Nakanishi Hideo, Nakata Isao, Akagi-Kurashige Yumiko, Tsujikawa Akitaka, Moriyama Muka, Ohno-Matsui Kyoko, Mochizuki Manabu, Yamada Ryo, Matsuda Fumihiko, Yoshimura Nagahisa

Abstract excerpt

PURPOSE: To investigate whether genetic variations in the insulin-like growth factor 1 (IGF-1) gene are associated with high myopia in Japanese. METHODS: A total of 1,339 unrelated Japanese patients with high myopia (axial length ≥26 mm in both eyes) and two independent control groups were evaluated (334 cataract patients without high myopia and 1,194 healthy Japanese individuals). The mean axial length (mm±SD)...

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PMID: 23734076
PMCID: PMC3668686

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