Article
High KIR diversity in Uganda and Botswana children living with HIV.
Human immunology - 1 Aug 2026
Mukisa John, Kyobe Samuel, Amujal Marion, Jacqueline Williams, Katagirya Eric, Diphoko Thabo, Sebetso Gaseene, Mwesigwa Savannah, Mboowa Gerald, Retshabile Gaone, Williams Lesedi, Mlotshwa Busisiwe, Matshaba Mogomotsi, Jjingo Daudi, Kateete David P, Joloba Moses L, Mardon Graeme, Hanchard Neil, Hollenbach Jill A
Abstract excerpt
Killer-cell immunoglobulin-like receptors (KIRs) are critical regulators of the innate immune system and are found on the surfaces of natural killer (NK) cells. The KIR encoding genes, located on chromosome 19q13.4, are genetically diverse and associated with HIV progression. However, there is limited knowledge on the diversity of KIR from Uganda and Botswana HIV-infected paediatric cohorts. We applied...
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