Article
Association between SCAP and SREBF1 gene polymorphisms and metabolic syndrome in schizophrenia patients treated with atypical antipsychotics.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Sept 2016
Yang Lin, Chen Jianhua, Li Yan, Wang Yan, Liang Shiqiao, Shi Yongyong, Shi Shenxun, Xu Yifeng
Abstract excerpt
OBJECTIVES: The use of atypical antipsychotics (AAPs) in the treatment of schizophrenia has been relevant because of the high prevalence of metabolic syndrome (MetS). The sterol-regulatory element-binding protein (SREBP) pathway may contribute to the underlying pathophysiology of AAP-induced metabolic adverse effects. We explored the association between the variants of the sterol-regulatory element-binding...
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