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Pharmacogenetic study of antipsychotic–induced lipid and BMI changes in Chinese schizophrenia patients: A Genome-Wide Association Study

19 Aug 2025

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Abstract Second-generation antipsychotics (SGAs) are widely used to treat schizophrenia (SCZ), but they often induce metabolic side effects like dyslipidemia and obesity. We conducted genome-wide association studies (GWASs) to identify genetic variants associated with SGA-induced lipid and BMI changes in Chinese SCZ patients. A longitudinal cohort of Chinese SCZ receiving SGAs was followed for up to 18.7 years...

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PMID: 40830362
DOI: 10.1038/s41398-025-03499-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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