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Article

Chromatin-wide and transcriptome profiling integration uncovers p38α MAPK as a global regulator of skeletal muscle differentiation.

Skeletal muscle - 1 Jan 2016

Segalés Jessica, Islam Abul B M M K, Kumar Roshan, Liu Qi-Cai, Sousa-Victor Pedro, Dilworth F Jeffrey, Ballestar Esteban, Perdiguero Eusebio, Muñoz-Cánoves Pura

Abstract excerpt

BACKGROUND: Extracellular stimuli induce gene expression responses through intracellular signaling mediators. The p38 signaling pathway is a paradigm of the mitogen-activated protein kinase (MAPK) family that, although originally identified as stress-response mediator, contributes to establishing stem cell differentiation fates. p38α is central for induction of the differentiation fate of the skeletal muscle stem...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26981231
DOI: 10.1186/s13395-016-0074-x
PMCID: PMC4791895

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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