Article
Efficient adult skeletal muscle regeneration in mice deficient in p38beta, p38gamma and p38delta MAP kinases.
Cell cycle (Georgetown, Tex.) - 15 Jul 2008
Ruiz-Bonilla Vanessa, Perdiguero Eusebio, Gresh Lionel, Serrano Antonio L, Zamora Mònica, Sousa-Victor Pedro, Jardí Mercè, Wagner Erwin F, Muñoz-Cánoves Pura
Abstract excerpt
Adult skeletal muscle is a very stable tissue containing a small population of myofiber-associated quiescent satellite cells compared with late embryonic/neonatal skeletal muscle, which contains highly proliferating myoblasts and small actively growing myofibers, suggesting that specific regulatory pathways may control myogenesis at distinct developmental stages. The p38 MAPK signaling pathway is central for...
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