Article
HLA-DQA1 and PLA2R1 polymorphisms and risk of idiopathic membranous nephropathy.
Clinical journal of the American Society of Nephrology : CJASN - 1 Feb 2014
Bullich Gemma, Ballarín José, Oliver Artur, Ayasreh Nadia, Silva Irene, Santín Sheila, Díaz-Encarnación Montserrat M, Torra Roser, Ars Elisabet
Abstract excerpt
BACKGROUND AND OBJECTIVES: Single nucleotide polymorphisms (SNPs) within HLA complex class II HLA-DQ α-chain 1 (HLA-DQA1) and M-type phospholipase A2 receptor (PLA2R1) genes were identified as strong risk factors for idiopathic membranous nephropathy (IMN) development in a recent genome-wide association study. Copy number variants (CNVs) within the Fc gamma receptor III (FCGR3) locus have been associated with...
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