Article
Is FCGR2A a susceptibility gene to systemic lupus erythematosus in Chinese?
Lupus - 1 Oct 2011
Zhou X J, Lv J C, Qin L X, Yang H Z, Yu F, Zhao M H, Zhang H
Abstract excerpt
Recent genome-wide association scans and replication studies reinforce that FCGR2A is a susceptibility gene in systemic lupus erythematosus (SLE) in Caucasians. However, previous case control studies denied such conclusions in Chinese people. Besides genetic heterogeneity among different ethnicities, copy number variation (CNV), non-homogenous phenotypes and insufficient power may be confounders. We performed a...
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