Article
Hsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis without increased bleeding risk.
Cardiovascular research - 1 Jun 2016
Allende Mikel, Molina Eva, Guruceaga Elisabet, Tamayo Ibai, González-Porras José Ramón, Gonzalez-López Tomás José, Toledo Estefanía, Rabal Obdulia, Ugarte Ana, Roldán Vanesa, Rivera José, Oyarzabal Julen, Montes Ramón, Hermida José
Abstract excerpt
AIMS: Atrial fibrillation (AF) is a major risk factor for cardio-embolic stroke. Anticoagulant drugs are effective in preventing AF-related stroke. However, the high frequency of anticoagulant-associated major bleeding is a major concern. This study sought to identify new targets to develop safer antithrombotic therapies. METHODS AND RESULTS: Here, microarray analysis in peripheral blood cells in eight patients...
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