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Article

HSP90 Family Members, Their Regulators and Ischemic Stroke Risk: A Comprehensive Molecular-Genetics and Bioinformatics Analysis.

Frontiers in bioscience (Scholar edition) - 11 Dec 2024

Kobzeva Ksenia, Ivenkov Maxim, Gromov Rostislav, Bushueva Olga

Abstract excerpt

BACKGROUND: Disruptions in proteostasis are recognized as key drivers in cerebro- and cardiovascular disease progression. Heat shock proteins (HSPs), essential for maintaining protein stability and cellular homeostasis, are pivotal in neuroperotection. Consequently, deepening the understanding the role of HSPs in ischemic stroke (IS) risk is crucial for identifying novel therapeutic targets and advancing...

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Case-Control Studies
Computational Biology
Heat Shock Transcription Factors
HSP90 Heat-Shock Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ischemic Stroke

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Identifiers

PMID: 39736019
DOI: 10.31083/j.fbs1604019

Genes

HSF2
HSP90AA1
HSPB8
HSF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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