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Article

The role of CHMP2BIntron5 in autophagy and frontotemporal dementia.

Brain research - 15 Oct 2016

Krasniak Christopher S, Ahmad S Tariq

Abstract excerpt

Charged multivesicular body protein 2B (CHMP2B) - a component of the endosomal complex required for transport-III (ESCRT-III) - is responsible for the vital membrane deformation functions in autophagy and endolysosomal trafficking. A dominant mutation in CHMP2B (CHMP2BIntron5) is associated with a subset of heritable frontotemporal dementia - frontotemporal dementia linked to chromosome 3 (FTD-3). ESCRT-III...

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Identifiers

PMID: 26972529
DOI: 10.1016/j.brainres.2016.02.051
PMCID: PMC5018243

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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