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Article

ESCRT, autophagy, and frontotemporal dementia.

BMB reports - 31 Dec 2008

Lee Jin-A, Gao Fen-Biao

Abstract excerpt

Many age-dependent neurodegenerative diseases are associated with the accumulation of abnormally folded proteins within neurons. One of the major proteolytic pathways in the cell is the autophagy pathway, which targets cytoplasmic contents and organelles to the lysosomes for bulk degradation under various physiological and stressful conditions. Although the importance of autophagy in cellular physiology is well...

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Identifiers

PMID: 19123971
DOI: 10.5483/bmbrep.2008.41.12.827

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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