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Article

Frontotemporal dementia caused by CHMP2B mutations.

Current Alzheimer research - 1 May 2011

Isaacs A M, Johannsen P, Holm I, Nielsen J E

Abstract excerpt

CHMP2B mutations are a rare cause of autosomal dominant frontotemporal dementia (FTD). The best studied example is frontotemporal dementia linked to chromosome 3 (FTD-3) which occurs in a large Danish family, with a further CHMP2B mutation identified in an unrelated Belgian familial FTD patient. These mutations lead to C-terminal truncations of the CHMP2B protein and we will review recent advances in our...

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Identifiers

PMID: 21222599
DOI: 10.2174/156720511795563764
PMCID: PMC3182073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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