Article
A fast expectation-maximum algorithm for fine-scale QTL mapping.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik - 1 Dec 2012
Fang Ming
Abstract excerpt
The recent technology of the single-nucleotide-polymorphism (SNP) array makes it possible to genotype millions of SNP markers on genome, which in turn requires to develop fast and efficient method for fine-scale quantitative trait loci (QTL) mapping. The single-marker association (SMA) is the simplest method for fine-scale QTL mapping, but it usually shows many false-positive signals and has low QTL-detection...
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