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Article

The VPS35 protein and the role of its impairments in mitochondrial dysfunction in Parkinson's disease.

Biomeditsinskaia khimiia - 1 Feb 2026

Buneeva O A, Medvedev A E

Abstract excerpt

The VPS35 is an essential protein that plays multifunctional roles in various biological processes. It is a core component of the retromer complex, involved in protein recycling from endosomes to the trans-Golgi network (TGN) and the plasma membrane. Besides its role as the retromer complex component, VPS35 interacts with many proteins and regulates mitochondrial homeostasis, mitochondrial dynamics (fusion and...

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Source

Identifiers

PMID: 41841708
DOI: 10.18097/PBMCR1648

Genes

VPS35

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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